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Supplementary Tables S1-S4 from IRS2 Copy Number Gain, KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
- Publication Year :
- 2023
- Publisher :
- American Association for Cancer Research (AACR), 2023.
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Abstract
- Supplementary Tables S1-S4. Supplementary Table S1: Association of gene mutations, IRS2 copy number gain, and gene expression level with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S2: The relationship between KRAS, BRAF and PIK3CA mutation status and the sensitivity of BMS-754807 in 60 CRC cell lines. Supplementary Table S3: Statistical analyses identified CNV of 197 genes located on chromosome 13 significantly associated with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S4: Data mining indicate IRS2 CNG is more prevalent in CRC than in other tumor types.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....faf361093d6982b4e2b58d163680e344