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Multifocal electroretinography and spectral-domain optical coherence tomography in macula-off rhegmatogenous retinal detachment: A prospective cohort study
- Source :
- RETINA, RETINA, Lippincott, Williams & Wilkins, 2021, 41 (4), pp.744-752. ⟨10.1097/iae.0000000000002939⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; Purpose: To analyze the temporal trends in structural changes using spectral-domain optical coherence tomography and functional changes using multifocal electroretinogram after rhegmatogenous retinal detachment surgery. Methods: This prospective cohort study enrolled 69 patients with macula-off rhegmatogenous retinal detachment who underwent successful surgery. Early Treatment Diabetic Retinopathy Study visual acuity, multifocal electroretinogram evaluation of the central 5 degrees, and spectral-domain optical coherence tomography were recorded at 1, 3, 6, and 12 months (M) after surgery. The fellow eye served as the control group for multifocal electroretinogram parameters. Results: Between M1 and M12, visual acuity improved from 64 to 75 letters (P = 0.001) and implicit time of N1 decreased from 27.8 to 25.2 milliseconds (P = 0.001), whereas the other parameters did not vary significantly. Amplitude and implicit time values did not reach normal values at M12. Alterations of the ellipsoid zone and the external limiting membrane decreased over time (P = 0.001). P1 implicit time correlated independently with the alteration of the external limiting membrane (P = 0.007). Conclusion: Foveal wave amplitudes remain lower than normal values after successful surgery of rhegmatogenous retinal detachment, whereas anatomical improvement was found for outer retinal abnormalities and subretinal edema fluid. Retinal recovery improves N1 implicit time over time. Disruption of external limiting membrane seems to be predictive of increased P1 implicit time.
- Subjects :
- Visual acuity
genetic structures
Visual Acuity
surgery
chemistry.chemical_compound
0302 clinical medicine
oct
Foveal
Vitrectomy
Macula Lutea
Prospective Studies
Prospective cohort study
External limiting membrane
visual-acuity
medicine.diagnostic_test
Retinal detachment
General Medicine
Diabetic retinopathy
Middle Aged
external limiting membrane
3. Good health
Scleral Buckling
medicine.anatomical_structure
spectral-domain optical coherence tomography
ellipsoid
medicine.symptom
Tomography, Optical Coherence
medicine.medical_specialty
retinal
Retina
Contrast Sensitivity
03 medical and health sciences
recovery
Optical coherence tomography
erg
Ophthalmology
medicine
Electroretinography
Humans
[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs
Aged
business.industry
Retinal Detachment
outer retina
Retinal
medicine.disease
sensitivity
eye diseases
chemistry
detachment
030221 ophthalmology & optometry
Visual Field Tests
sense organs
multifocal electroretinogram
Visual Fields
business
030217 neurology & neurosurgery
fovea
Subjects
Details
- Language :
- English
- ISSN :
- 0275004X
- Database :
- OpenAIRE
- Journal :
- RETINA, RETINA, Lippincott, Williams & Wilkins, 2021, 41 (4), pp.744-752. ⟨10.1097/iae.0000000000002939⟩
- Accession number :
- edsair.doi.dedup.....fad7ea8ad7a8262d6a26f73665400b3b