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Hemograms and serial hemogram-derived ratios in survivors and non-survivors of COVID-19 in Campinas, Brazil

Authors :
Adekunle Emmanuel Alagbe
Gisele Audrei Pedroso
Beatriz Benedetti de Oliveira
Edivilson da Costa
Gisélia Aparecida Freire Maia
Bruna Facanali Piellusch
Susan Elisabeth Domingues Costa Jorge
Fernando Ferreira Costa
José Luiz Proença Modena
Angelica Zaninelli Schreiber
Maria de Fátima Sonati
Magnun Nueldo Nunes Santos
Source :
Hematology, transfusion and cell therapy.
Publication Year :
2022

Abstract

The hemogram and hemogram-derivative ratios (HDRs) are becoming markers of the severity and mortality of COVID-19. We evaluated the hemograms and serial weekly HDRs [neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), neutrophil-platelet ratio (NPR) and systemic immune-inflammatory index (SII)] in the survivors and non-survivors of COVID-19.We retrospectively reviewed the medical notes and serial hemograms of real-time reverse-transcription polymerase chain reaction (RT-PCR)-confirmed COVID-19 adults hospitalized from April 2020 to March 2021 from the time of diagnosis to the 3Of the 320 adults, 257 (80.3%) were survivors and had a lower mean age than the non-survivors (57.73This study shows that serial lymphocyte and neutrophil counts, NLR, PLR, MLR, NPR and SII could serve as good and easily accessible markers of severity and predictors of outcomes in COVID-19 patients and should be used for the monitoring of treatment response.

Subjects

Subjects :
Immunology and Allergy
Hematology

Details

ISSN :
25311387
Database :
OpenAIRE
Journal :
Hematology, transfusion and cell therapy
Accession number :
edsair.doi.dedup.....fac39fa76022526cf21eb39cb4e7beda