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Patterns and Correlates of Baseline Thiazide-Type Diuretic Prescription in the Systolic Blood Pressure Intervention Trial
- Source :
- Hypertension. 67:550-555
- Publication Year :
- 2016
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2016.
-
Abstract
- Thiazides and thiazide-type diuretics are recommended as first-line agents for the treatment of hypertension, but contemporary information on their use in clinical practice is lacking. We examined patterns and correlates of thiazide prescription in a cross-sectional analysis of baseline data from participants enrolled in the Systolic Blood Pressure Intervention Trial (SPRINT). We examined baseline prescription of thiazides in 7582 participants receiving at least 1 antihypertensive medication by subgroup, and used log-binomial regression to calculate adjusted prevalence ratios for thiazide prescription (versus no thiazide). Forty-three percent of all participants were prescribed a thiazide at baseline, but among participants prescribed a single agent, the proportion was only 16%. The prevalence of thiazide prescription differed significantly by demographic factors, with younger participants, women, and blacks all having higher adjusted prevalence of thiazide prescription than other corresponding subgroups. Participants in the lowest category of kidney function (estimated glomerular filtration rate
- Subjects :
- Male
medicine.medical_specialty
Prescription Drugs
Systole
Cross-sectional study
Sodium Chloride Symporter Inhibitors
medicine.medical_treatment
Renal function
Blood Pressure
030204 cardiovascular system & hematology
Article
03 medical and health sciences
0302 clinical medicine
Internal medicine
Internal Medicine
medicine
Humans
030212 general & internal medicine
Medical prescription
Thiazide
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Retrospective cohort study
Middle Aged
medicine.disease
Cross-Sectional Studies
Treatment Outcome
Endocrinology
Blood pressure
Hypertension
Female
Diuretic
business
Follow-Up Studies
Kidney disease
medicine.drug
Subjects
Details
- ISSN :
- 15244563 and 0194911X
- Volume :
- 67
- Database :
- OpenAIRE
- Journal :
- Hypertension
- Accession number :
- edsair.doi.dedup.....fabb1e3a0b30cebed2a685f1bbfe267f