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Electrocardiographic Strain Pattern Is a Major Determinant of Rehospitalization for Heart Failure After Transcatheter Aortic Valve Replacement
- Source :
- Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Journal of the American Heart Association, Journal of the American Heart Association, 2021, 10 (3), pp.e014481. ⟨10.1161/JAHA.119.014481⟩
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- Background Electrocardiographic strain pattern (ESP) has recently been associated with increased adverse outcome in aortic stenosis and after surgical aortic valve replacement. Our study sought to determine the impact and incremental value of ESP pattern in predicting adverse outcome after transcatheter aortic valve replacement. Methods and Results A total of 585 patients with severe aortic stenosis (mean age, 83±7 years; men, 39.8%) were enrolled for transcatheter aortic valve replacement from November 2012 to May 2018. ESP was defined as ≥1‐mm concave down‐sloping ST‐segment depression and asymmetrical T‐wave inversion in the lateral leads. The primary end points of the study were all‐cause mortality, rehospitalization for heart failure, myocardial infarction, and stroke. A total of 178 (30.4%) patients were excluded because of left bundle‐branch block (n=103) or right bundle‐branch block (n=75). Among the 407 remaining patients, 106 had ESP (26.04%). At a median follow‐up of 20.00 months (11.70–29.42 months), no impact of electric strain on overall and cardiac death could be established. By contrast, incidence of rehospitalization for heart failure was significantly higher (33/106 [31.1%] versus 33/301 [11%]; P P Conclusions In patients with aortic stenosis who were eligible for transcatheter aortic valve replacement, ESP is frequent and associated with an increased risk of postinterventional heart failure regardless of preoperative left ventricular hypertrophy. ESP represents an easy, objective, reliable, and low‐cost tool to identify patients who may benefit from intensified postinterventional follow‐up.
- Subjects :
- [SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery
medicine.medical_treatment
030204 cardiovascular system & hematology
Severity of Illness Index
Electrocardiography
fluids and secretions
Postoperative Complications
0302 clinical medicine
transcutaneous aortic valve implantation
Aortic valve replacement
Valve replacement
Catheter-Based Coronary and Valvular Interventions
Risk Factors
Postoperative Period
030212 general & internal medicine
Original Research
Aged, 80 and over
Prognosis
[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Echocardiography
Cardiology
[SDV.IB]Life Sciences [q-bio]/Bioengineering
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Transcatheter aortic
Adverse outcomes
[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery
Patient Readmission
Transcatheter Aortic Valve Replacement
03 medical and health sciences
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Internal medicine
medicine
Humans
Retrospective Studies
[SDV.IB] Life Sciences [q-bio]/Bioengineering
Heart Failure
business.industry
aortic stenosis
Aortic Valve Stenosis
medicine.disease
Myocardial Contraction
Stenosis
Strain pattern
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
Valvular Heart Disease
Heart failure
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 20479980
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Journal of the American Heart Association
- Accession number :
- edsair.doi.dedup.....fa9342da87363c4ebbf49a088f10b1e7