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Morphometry Confirms Fibrosis Regression From Sustained Virologic Response to Direct-Acting Antivirals for Hepatitis C
- Source :
- Hepatology Communications, Hepatology Communications, Vol 2, Iss 11, Pp 1320-1330 (2018)
- Publication Year :
- 2018
-
Abstract
- Sustained virologic response (SVR) after direct-acting antiviral (DAA) therapy for chronic hepatitis C results in significant decreases in liver stiffness measured by transient elastography (TE). The aim of this study was to clarify if TE can guide post-SVR management in patients with advanced fibrosis or cirrhosis prior to treatment as current guidelines are unclear on the role of TE after SVR. In total, 84 patients with hepatitis C virus and advanced fibrosis or cirrhosis and from a single center underwent DAA treatment and achieved SVR. Overall, 62% had improved liver stiffness that was consistent with regression of at least one stage of fibrosis. In the cirrhosis group, 48% showed fibrosis regression by at least two stages by TE (
- Subjects :
- medicine.medical_specialty
Cirrhosis
Hepatitis C virus
medicine.disease_cause
Single Center
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Fibrosis
Internal medicine
Biopsy
medicine
lcsh:RC799-869
Hepatology
medicine.diagnostic_test
business.industry
virus diseases
Hepatitis C
Original Articles
medicine.disease
Regression
digestive system diseases
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
lcsh:Diseases of the digestive system. Gastroenterology
Original Article
business
Transient elastography
Subjects
Details
- ISSN :
- 2471254X
- Volume :
- 2
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Hepatology communications
- Accession number :
- edsair.doi.dedup.....fa8aacf472fd98c9cb9a222840fc8ddd