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Experimental (Re)structuring: The Clinical Trial as Turning Point Among Medical Research Participants
- Source :
- Qual Health Res
- Publication Year :
- 2021
- Publisher :
- SAGE Publications, 2021.
-
Abstract
- Amid the growth of addiction medicine randomized controlled trials (RCTs), scholars have begun examining participants’ study experiences, highlighting facilitators and barriers to enrollment. However, this work can overlook the interplay between trial participation and social-structural dimensions among people with substance use disorders linked to the social nature of use, socioeconomic marginalization, and time demands of substance procurement and use. To effectively conduct RCTs with this unique population, it is necessary to examine the broader social context of study participation. We conducted nested qualitative interviews with 22 participants involved in an RCT testing a treatment for alcohol and opioid use disorders in HIV clinics. Thematic analyses revealed social-structural circumstances shaping RCT participation as well as how participation constitutes a turning point, prompting individuals to reconfigure social networks, reorient to spatial environments, and reorganize day-to-day life—with implications for how substance use disorder RCTs should be approached by researchers.
- Subjects :
- Biomedical Research
Population
Social Environment
0603 philosophy, ethics and religion
Article
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
medicine
Humans
030212 general & internal medicine
education
Socioeconomic status
Qualitative Research
education.field_of_study
Social nature
Public Health, Environmental and Occupational Health
Social environment
06 humanities and the arts
Opioid-Related Disorders
medicine.disease
Research Personnel
3. Good health
Clinical trial
Substance abuse
Addiction medicine
060301 applied ethics
Psychology
Clinical psychology
Subjects
Details
- ISSN :
- 15527557 and 10497323
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Qualitative Health Research
- Accession number :
- edsair.doi.dedup.....fa40fbcd50868ddb79c8bc28bc8fc3f6