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Tubarial gland involvement in IgG4-related diseases
- Source :
- Acta Oto-Laryngologica. 142:616-619
- Publication Year :
- 2022
- Publisher :
- Informa UK Limited, 2022.
-
Abstract
- Tubarial glands (TGs) are a collection of unidentified salivary glands overlying the torus tubarius in the nasopharyngeal wall. Immunoglobulin G4-related disease (IgG4-RD) is a chronic fibroinflammatory state that often has multiple organ involvement. Involvement of the head and neck, especially the salivary glands, is common in IgG4-RD.This study aimed to elucidate the clinical significance of TGs in IgG4-RD.We investigated the local findings of TGs in ten patients with IgG4-RD.Nasopharyngeal endoscopic examination revealed oedematous swelling of the nasopharyngeal wall surrounding the TGs, which improved after steroid treatment. Moreover, sonotubometry showed a stenotic pattern in three out of seven patients with IgG4-RD.TGs may be involved in IgG4-RD. The swollen TGs may be responsible for obstructive Eustachian tube dysfunction. Further studies are required to clarify the clinical significance and physiological roles of TGs in IgG4-RD.
Details
- ISSN :
- 16512251 and 00016489
- Volume :
- 142
- Database :
- OpenAIRE
- Journal :
- Acta Oto-Laryngologica
- Accession number :
- edsair.doi.dedup.....fa1a25e79cb282dca4c5f56bf9fa3859