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Is There a Contribution of Structural Brain Phenotypes to the Variance in Resting Energy Expenditure before and after Weight Loss in Overweight Females?
- Source :
- Nutrients, Volume 11, Issue 11
- Publication Year :
- 2019
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2019.
-
Abstract
- Brain gray (GM) and white matter (WM) are associated with resting energy expenditure (REE). The impact of weight loss on GM and WM masses, as well as on their associations with REE and the ratio between body and brain metabolism, i.e., encephalic measure (EM)), are unknown. Longitudinal data of 69 female Caucasian subjects (age range 19&ndash<br />69 years) with detailed information on fat mass (FM), fat free mas (FFM), GM, WM and REE. Mean weight loss was 14.5 &plusmn<br />11.9 kg with changes in FM (&minus<br />12.9 &plusmn<br />9.8 kg), FFM (&minus<br />1.7 &plusmn<br />4.8 kg) and REE (&minus<br />159 &plusmn<br />191 kcal/24 h) (all p &lt<br />0.05). With weight loss, there were no changes in GM and WM. Before and after weight loss, FFM was the main determinant of REE (r2 = 0.483 and 0.413<br />p &lt<br />0.05). After weight loss, GM added to the variances in REE (3.6%), REEadjFFM (6.1%) and the REE on FFM residuals (6.6%). In addition, before and after weight loss GM explained 25.0% and 10.0% of the variances in EM (p &lt<br />0.05). Weight loss had no effect on volumes of GM and WM. After weight loss, both, GM added to the variances of REE, REE on FFM residuals and EM.
- Subjects :
- Adult
Longitudinal data
Rest
brain
030209 endocrinology & metabolism
Overweight
Biology
White People
Article
Fat mass
03 medical and health sciences
Young Adult
0302 clinical medicine
Animal science
Weight loss
medicine
Humans
Resting energy expenditure
Obesity
Aged
Nutrition and Dietetics
Fluid compartments
Body Fluid Compartments
Organ Size
gray matter
Middle Aged
medicine.disease
resting energy expenditure
Phenotype
Adipose Tissue
Basal metabolic rate
Body Composition
Female
Basal Metabolism
medicine.symptom
weight loss
white matter
030217 neurology & neurosurgery
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 20726643
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....f9f2b4152e8e6c93a65de6bc7ece1e32
- Full Text :
- https://doi.org/10.3390/nu11112759