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Chemistry and weak antimicrobial activities of phomopsins produced by mangrove endophytic fungus Phomopsis sp. ZSU-H76
- Source :
- Phytochemistry. 69(7)
- Publication Year :
- 2007
-
Abstract
- Three metabolites named phomopsin A (1), B (2) and C (3), together with two known compounds cytosporone B (4) and C (5), were isolated from the mangrove endophytic fungus, Phomopsis sp. ZSU-H76 obtained from the South China Sea. Their structures were elucidated by spectroscopic methods, mainly by 1D and 2D NMR spectroscopic techniques. The medium-sized cyclic phenol ether based on 1 or 2 is rare in natural products. In bioassays, compounds 1, 2, and 3 had no significant antibiotic activities, but compounds 4 and 5 inhibited two fungi Candida albicans and Fusarium oxysporum with an MIC ranging from 32 to 64 microg/ml.
- Subjects :
- Fusarium
Magnetic Resonance Spectroscopy
Plant Science
Microbial Sensitivity Tests
Horticulture
Excoecaria agallocha
Biochemistry
chemistry.chemical_compound
Ascomycota
Fusarium oxysporum
Botany
Candida albicans
Phenols
Molecular Biology
biology
Molecular Structure
General Medicine
Mycotoxins
biology.organism_classification
Antimicrobial
Anti-Bacterial Agents
chemistry
Phomopsis
Avicennia
Subjects
Details
- ISSN :
- 00319422
- Volume :
- 69
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Phytochemistry
- Accession number :
- edsair.doi.dedup.....f96b20492d835b44a51af6c90d2a6bc3