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Cervical cancer screening with cervicography and cytology
- Source :
- European journal of obstetrics, gynecology, and reproductive biology. 58(1)
- Publication Year :
- 1995
-
Abstract
- The results of colposcopy and directed biopsies were compared with the cytological findings and cervicography in 1539 asymptomatic outpatients undergoing routine cervical cancer screening in order to compare the accuracy of cervicography and cytology and to assess the potential benefits of the combination of both screening tests. With the new reporting criteria, cervicography looked less sensitive (53% vs. 56%; P = 0.718) and significantly less specific (97% vs. 98%; P = 0.040) than cytology. In comparison with cytology and at the expense of a recall rate of 9%, the combination of both screening tests and to an increase of the sensitivity (77% vs. 56%; P = 0.013) but also to a decrease of the specificity (95% vs. 98%; P0.0001) and of the positive predictive value (44% vs. 60%; P = 0.051). When the original reporting criteria were applied to cervicography, the combination of both screening tests led to optimal sensitivity and negative predictive value (100%, respectively) at the expense of an unrealistic recall rate of 20%. Consequently, cervicography should not be considered as an alternative to cytology for cervical cancer screening since its accuracy is not significantly better and its rate of technically defective tests is significantly higher. The combination of both methods increases the sensitivity of cervical cancer screening at the expense of a high recall rate, of which cost effectiveness has to be assessed.
- Subjects :
- Adult
medicine.medical_specialty
Adolescent
Cost effectiveness
Biopsy
Cytological Techniques
Uterine Cervical Neoplasms
Cervix Uteri
Cervical cancer screening
Asymptomatic
Sensitivity and Specificity
Predictive Value of Tests
Cytology
medicine
Photography
Humans
Mass Screening
Prospective Studies
Aged
Gynecology
Colposcopy
Cervical cancer
Aged, 80 and over
Vaginal Smears
medicine.diagnostic_test
Obstetrics
business.industry
Obstetrics and Gynecology
Middle Aged
medicine.disease
Reproductive Medicine
Female
medicine.symptom
Cervicography
Recall rate
business
Subjects
Details
- ISSN :
- 03012115
- Volume :
- 58
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- European journal of obstetrics, gynecology, and reproductive biology
- Accession number :
- edsair.doi.dedup.....f956aa98d98887829e7cb439c3219427