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Identification of 11β-HSD1 inhibitors through enhanced sampling methods

Authors :
Rahul Singh
Vijay Kumar Bhardwaj
Pralay Das
Rituraj Purohit
Source :
Chemical communications (Cambridge, England). 58(32)
Publication Year :
2022

Abstract

Aminoarylbenzosuberene (AAB) molecules were chosen for in silico analysis to develop effective and more competent 11β-hydroxysteroid dehydrogenase (11β-HSD1) protein inhibitors.

Subjects

Subjects :
11-beta-Hydroxysteroid Dehydrogenase Type 1
Materials Chemistry
Metals and Alloys
Ceramics and Composites
General Chemistry
Enzyme Inhibitors
hormones, hormone substitutes, and hormone antagonists
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials

Details

ISSN :
1364548X
Volume :
58
Issue :
32
Database :
OpenAIRE
Journal :
Chemical communications (Cambridge, England)
Accession number :
edsair.doi.dedup.....f95153395d026c89a9f07631de053a7a

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