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Use of zidovudine-sparing HAART in pregnant HIV-infected women in Europe: 2000-2009
- Source :
- Journal of acquired immune deficiency syndromes (1999), 57(4), 326-333. Lippincott Williams and Wilkins
- Publication Year :
- 2011
-
Abstract
- Increasing numbers of women in resource-rich settings are prescribed zidovudine (ZDV)-sparing highly active antiretroviral therapy (HAART) in pregnancy. We compare ZDV-sparing with ZDV-containing HAART in relation to maternal viral load at delivery, mother-to-child transmission (MTCT) of HIV, and congenital abnormality. This is an analysis of data from the National Study of HIV in Pregnancy and Childhood and the European Collaborative Study. Data on 7573 singleton births to diagnosed HIV-infected women between January 2000 and June 2009 were analyzed. Logistic regression models were fitted to estimate adjusted odds ratios (AORs). Overall, 15.8% (1199 of 7573) of women received ZDV-sparing HAART, with increasing use between 2000 and 2009 (P
- Subjects :
- Adult
Pediatrics
medicine.medical_specialty
Time Factors
HAART
Anti-HIV Agents
HIV Infections
antiretroviral agents
highly active antiretroviral therapy
HIV
pregnancy outcome
viral load
congenital abnormalities
Article
Zidovudine
ANTIRETROVIRAL AGENTS
immune system diseases
Hiv infected
Antiretroviral Therapy, Highly Active
Medicine
Humans
Pharmacology (medical)
Pregnancy Complications, Infectious
antiretroviral agents, highly active antiretroviral therapy, HIV, pregnancy outcome, viral load
Pregnancy outcomes
Retrospective Studies
Pregnancy
integumentary system
business.industry
Infant
virus diseases
Retrospective cohort study
medicine.disease
Infectious Disease Transmission, Vertical
CD4 Lymphocyte Count
zidovudine
Europe
Infectious Diseases
In utero
Immunology
Female
pregnancy
business
Viral load
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 15254135
- Volume :
- 57
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of acquired immune deficiency syndromes (1999)
- Accession number :
- edsair.doi.dedup.....f94adb67d9c2efe6c343a2e43600d056