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The effect of wavelength on glial fibrillary acidic protein immunoreactivity in laser-induced lesions in rabbit retina
- Source :
- Graefe's Archive for Clinical and Experimental Ophthalmology. 229:380-388
- Publication Year :
- 1991
- Publisher :
- Springer Science and Business Media LLC, 1991.
-
Abstract
- Rabbit retinas were treated with low-intensity laser coagulation at five different wavelengths. Using an indirect immunocytochemical method, the retinas were stained for glial fibrillary acidic protein (GFAP) at 2, 4, 21 and 32 days after coagulation such that we could follow GFAP expression in the Müller cells during retinal repair. GFAP-positive staining was found in the end feet of the Müller cells at 2 days after laser coagulation. GFAP immunoreactivity was observed throughout the Müller cells, surrounding the central necrotic tissue, at days 4, 21 and 32 after laser coagulation. Scar tissue in the subretinal space at days 21 and 32, which was more pronounced for the longer wavelengths produced by the Krypton and Nd-YAG lasers, also showed GFAP immunoreactivity. The Müller cells remained GFAP-immunoreactive for at least 32 days after laser coagulation.
- Subjects :
- Pathology
medicine.medical_specialty
medicine.medical_treatment
Light Coagulation
Retina
Immunoenzyme Techniques
Cellular and Molecular Neuroscience
chemistry.chemical_compound
Retinal Diseases
Glial Fibrillary Acidic Protein
medicine
Animals
Wound Healing
Lagomorpha
biology
Glial fibrillary acidic protein
Lasers
Retinal
Anatomy
GFAP stain
biology.organism_classification
Sensory Systems
Staining
Ophthalmology
medicine.anatomical_structure
nervous system
chemistry
biology.protein
Immunohistochemistry
Rabbits
sense organs
Laser coagulation
Subjects
Details
- ISSN :
- 1435702X and 0721832X
- Volume :
- 229
- Database :
- OpenAIRE
- Journal :
- Graefe's Archive for Clinical and Experimental Ophthalmology
- Accession number :
- edsair.doi.dedup.....f91c288c9195c5bc53c9de43b7db0a0f