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Evolving role of minimally invasive techniques in the management of symptomatic bone metastases
- Source :
- Current Opinion in Supportive & Palliative Care. 15:91-98
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- Purpose of review Bone metastases are responsible for considerable morbidity, which can significantly limit a patient's quality of life. This article aims to review minimally invasive, image-guided locoregional treatments for symptomatic bone metastases as an adjunct to conventional treatment modalities. Recent findings Conservative therapy and radiation therapy (RT) can be effective at addressing pain, however, they require time to achieve optimal efficacy and do not address the instability and progressive collapse of pathological fractures. Vertebral and pelvic augmentation with cement enhances structural stability and can prevent progressive collapse and deformity. Ablative therapies, including radiofrequency ablation (RFA), cryoablation, and photodynamic therapy (PDT), induce cellular destruction of tumor tissue. RFA and PDT can be combined with cement augmentation in a single sitting. Summary Minimally invasive image-guided treatments can provide rapid pain relief, enhance mechanical stability, and improve quality of life. These treatments are associated with low complication rates and are suitable for frail patients. They can be used as companion procedures to conventional treatments, or function as an alternative for patients with radioresistant biologies or those with dose limitations from prior RT sessions.
- Subjects :
- medicine.medical_specialty
Radiofrequency ablation
medicine.medical_treatment
Pain
Photodynamic therapy
Critical Care and Intensive Care Medicine
law.invention
03 medical and health sciences
0302 clinical medicine
Quality of life
law
Ablative case
Deformity
medicine
Humans
Pain Management
030212 general & internal medicine
Radiofrequency Ablation
Spinal Neoplasms
Oncology (nursing)
business.industry
food and beverages
Cryoablation
General Medicine
Radiation therapy
030228 respiratory system
Oncology
Quality of Life
Radiology
medicine.symptom
Complication
business
Subjects
Details
- ISSN :
- 17514266 and 17514258
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Current Opinion in Supportive & Palliative Care
- Accession number :
- edsair.doi.dedup.....f91acbe9f7620639c1bf49651ffb94da