Effectiveness of isotretinoin in preventing the appearance of basal cell carcinomas in basal cell nevus syndrome

Fig. 1. Number of lesions in identical twins with basal cell nevus syndrome during isotretinoin therapy. REFERENCES 1. Haustein UF, Herrmann K, Bohme HJ. Pathogenesis of progressive systemic sclerosis. Int J Dermatol 1986;25:28693. 2. Cipoletti HF, Buckingham RB, Barnes EL, et al. Sjogren's syndrome in progressive systemic sclerosis. Ann Intern Med 1977;87:535-41. 3. Fong PH, Chan HL. Systemic lupus erythematosus with pemphigus vulgaris. Arch Dermato1 1985;121:26-7. 4. Vetters JM, Saikia NK, Wood J, et al. Pemphigus vulgaris and myasthenia gravis. Br J Derrnatol 1973;88:437-41. 5. Katz AL, Nashel DJ, Goard PG, et al. Pemphigus vulgaris and lymphoma in a patient with scleroderma. South Med J 1979;72:1463-6. 6. Heyden W. Pemphigus Seborrheicus bei progressiver Sklerodermie. Z Hautkr 1984;59:1336-9. pathogenetic mechanisms, or the association might be merely a coincidence. A larger series of patients should be reported and more should be learned about the pathogenetic mechanisms of these diseases before further conclusions are reached.