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Biologic and Synthetic Grafts in the Reconstruction of Large to Massive Rotator Cuff Tears
- Source :
- J Am Acad Orthop Surg
- Publication Year :
- 2016
-
Abstract
- Rotator cuff injuries are common in both young and elderly patients. Despite improvements in instrumentation and surgical techniques, the failure rates following tendon reconstruction remain unacceptably high. To improve outcomes, graft patches have been developed to provide mechanical strength and to furnish a scaffold for biologic growth across the delicate tendon-bone junction. Although no patch effectively re-creates the structured, highly organized system of prenatal tendon development, augmenting rotator cuff repair may help restore native tendon-to-bone attachment while reproducing the mechanical and biologic properties of native tendon. An understanding of biologically and synthetically derived grafts, along with knowledge of the preliminary data available regarding their combined use with growth factors and stem cells, is needed to improve management and treatment outcomes. The current literature has not been consistent in showing patch augmentation to be beneficial over traditional repair, but novel scaffolding materials may help facilitate rotator cuff tendon repair that is histologically and biomechanically comparable to native tendon.
- Subjects :
- Scaffold
medicine.medical_specialty
Combined use
Transplantation, Heterologous
Tendon reconstruction
Article
Rotator Cuff Injuries
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Transplantation, Homologous
Orthopedics and Sports Medicine
Rotator cuff
Orthopedic Procedures
030222 orthopedics
Tissue Scaffolds
business.industry
Guided Tissue Regeneration
Rotator cuff injury
030229 sport sciences
medicine.disease
musculoskeletal system
Tendon
Surgery
Extracellular Matrix
Transplantation
medicine.anatomical_structure
Tears
Collagen
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- J Am Acad Orthop Surg
- Accession number :
- edsair.doi.dedup.....f90d1b93d75ccd575cd95255685e80c4