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Prevalence and Risk Factors of Epiretinal Membranes in a Chinese Population: The Kailuan Eye Study
- Source :
- Investigative Ophthalmology & Visual Science
- Publication Year :
- 2020
- Publisher :
- Association for Research in Vision and Ophthalmology (ARVO), 2020.
-
Abstract
- Purpose To investigate the prevalence of epiretinal membranes (ERMs) and their risk factors in a Chinese population. Methods The community-based Kailuan Eye Study included 14,440 participants (9835 male, 4605 female) with a mean age of 54.0 ± 13.3 years (range, 20-110 years). They underwent a systemic and ophthalmologic examination. ERMs were diagnosed on fundus photographs. Results Retinal photographs assessable for the presence of ERMs were available for 13,295 (92.0%) individuals (9094 male) with a mean age of 53.6 ± 13.3 years (range, 20-110 years). ERMs were found in 1013 participants (1489 eyes) with a prevalence of 7.6% (95% confidence interval [CI], 7.1%-8.1%). Secondary ERMs caused by intraocular reasons were found 46 (4.5%) individuals (69 [4.6%] eyes). A higher prevalence of any ERMs (and of primary ERMs) was associated with older age (odds ratio [OR]: 1.08; 95% CI:1.07-1.10), higher body mass index (OR: 1.05; 95% CI: 1.00-1.11), higher prevalence of smoking (OR:1.43; 95% CI: 1.01-2.03), higher serum concentration of glucose (OR: 1.08; 95% CI: 1.04-1.13), and lower serum concentration of uric acid (OR: 0.99; 95% CI: 0.99-1.00). Visual acuity was significantly (P = 0.002) lower in eyes with premacular fibroses than in eyes with cellophane macular reflexes. Conclusions In our cross-sectional community-based study, the prevalence of all ERMs was 7.6%. Among the group of participants with ERMs, secondary ERMs caused by intraocular reasons were detected in 46 (4.5%) individuals (69 [4.6%] eyes). A higher prevalence of any ERM and of primary ERMs was associated with older age, higher body mass index, higher prevalence of smoking, a higher serum concentration of glucose, and a lower serum concentration of uric acid.
- Subjects :
- Adult
Male
China
medicine.medical_specialty
Visual acuity
genetic structures
prevalence
Visual Acuity
Fundus (eye)
ERMs
Young Adult
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Risk Factors
Internal medicine
Humans
Medicine
Aged
Aged, 80 and over
business.industry
Clinical and Epidemiologic Research
Epiretinal Membrane
Odds ratio
Middle Aged
medicine.disease
Confidence interval
Chinese people
Cross-Sectional Studies
risk factor
chemistry
Population Surveillance
030221 ophthalmology & optometry
Uric acid
Female
medicine.symptom
Epiretinal membrane
business
Body mass index
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15525783
- Volume :
- 61
- Database :
- OpenAIRE
- Journal :
- Investigative Opthalmology & Visual Science
- Accession number :
- edsair.doi.dedup.....f8d86be3319dd1d086740e09ba6dde44