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Production and Structural Analysis of Membrane-Anchored Proteins in Phospholipid Nanodiscs
- Source :
- Chem. Eur. J. 24, 5493-5499 (2018)
- Publication Year :
- 2018
-
Abstract
- Purpose of Review Advances in technology have expanded telemedicine opportunities covering medical practice, research, and education. This is of particular importance in movement disorders (MDs), where the combination of disease progression, mobility limitations, and the sparse distribution of MD specialists increase the difficulty to access. In this review, we discuss the prospects, challenges, and strategies for telemedicine in MDs.Recent Findings Telemedicine for MDs has been mainly evaluated in Parkinson's disease (PD) and compared to in-office care is cost-effective with similar clinical care, despite the barriers to engagement. However, particular groups including pediatric patients, rare MDs, and the use of telemedicine in underserved areas need further research.Summary Interdisciplinary telemedicine and tele-education for MDs are feasible, provide similar care, and reduce travel costs and travel time compared to in-person visits. These benefits have been mainly demonstrated for PD but serve as a model for further validation in other movement disorders.
- Subjects :
- 0301 basic medicine
Functional role
Models, Molecular
Protein Conformation
Lipid Bilayers
Phospholipid
010402 general chemistry
01 natural sciences
Catalysis
03 medical and health sciences
chemistry.chemical_compound
hemic and lymphatic diseases
Nuclear Magnetic Resonance, Biomolecular
Phospholipids
Protein function
Chemistry
Organic Chemistry
Membrane Proteins
General Chemistry
Nuclear magnetic resonance spectroscopy
Transmembrane protein
0104 chemical sciences
Nanostructures
Apoptosis
Membrane
Nanodiscs
Nmr Spectroscopy
Sortasea
030104 developmental biology
Solubilization
Helix
Biophysics
Hydrophobic and Hydrophilic Interactions
Subjects
Details
- ISSN :
- 15213765
- Volume :
- 24
- Issue :
- 21
- Database :
- OpenAIRE
- Journal :
- Chemistry (Weinheim an der Bergstrasse, Germany)
- Accession number :
- edsair.doi.dedup.....f8cf97023a3f97e9866d7188f7886d83