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Clinical characteristics and outcomes of patients with pediatric acute lymphoblastic leukemia after induction of chemotherapy: a pilot descriptive correlational study from Palestine
- Source :
- BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021), BMC Research Notes
- Publication Year :
- 2021
- Publisher :
- BMC, 2021.
-
Abstract
- Objective Pediatric acute lymphoblastic leukemia (ALL) is the most prevalent type of cancer among children. This study was conducted to describe and correlate the clinical characteristics and outcomes of treatment of patients with pediatric ALL in the main referral hospital in Palestine. Results Complete data of 69 patients were included in this analysis. The majority (79.7%) of the patients had B-ALL phenotype. After induction chemotherapy, remission was experienced by the vast majority of the patients and 5 (7.2%) experienced relapses. Cytogenetics for patients with B-ALL phenotype indicated that 10 (18.2%) patients had t(12, 21) translocation, 5 (9.1%) had hyperdiploidy, 4 (7.3%) had t(1, 19) translocation, and 2 (3.6%) had t(9, 22) translocation. The initial white blood cells (p value
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Palestine
Science (General)
Neutrophils
QH301-705.5
medicine.medical_treatment
Translocation
Chromosomal translocation
Acute lymphoblastic leukemia
General Biochemistry, Genetics and Molecular Biology
Translocation, Genetic
03 medical and health sciences
Leukocyte Count
Q1-390
0302 clinical medicine
Pediatric Acute Lymphoblastic Leukemia
Internal medicine
Medicine
Humans
Biology (General)
Child
Chemotherapy
business.industry
Remission Induction
Cytogenetics
Cancer
Induction chemotherapy
General Medicine
Precursor Cell Lymphoblastic Leukemia-Lymphoma
medicine.disease
Treatment
Research Note
030104 developmental biology
030220 oncology & carcinogenesis
Hyperdiploidy
business
Subjects
Details
- Language :
- English
- ISSN :
- 17560500
- Volume :
- 14
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Research Notes
- Accession number :
- edsair.doi.dedup.....f8b7d88e5026e8617cd0ea63dce907ed