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Clinical characteristics and outcomes of patients with pediatric acute lymphoblastic leukemia after induction of chemotherapy: a pilot descriptive correlational study from Palestine

Authors :
Ramzi Shawahna
Sultan Mosleh
Majd Al-Ghoul
Yahya Odeh
Rami Halawa
Source :
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021), BMC Research Notes
Publication Year :
2021
Publisher :
BMC, 2021.

Abstract

Objective Pediatric acute lymphoblastic leukemia (ALL) is the most prevalent type of cancer among children. This study was conducted to describe and correlate the clinical characteristics and outcomes of treatment of patients with pediatric ALL in the main referral hospital in Palestine. Results Complete data of 69 patients were included in this analysis. The majority (79.7%) of the patients had B-ALL phenotype. After induction chemotherapy, remission was experienced by the vast majority of the patients and 5 (7.2%) experienced relapses. Cytogenetics for patients with B-ALL phenotype indicated that 10 (18.2%) patients had t(12, 21) translocation, 5 (9.1%) had hyperdiploidy, 4 (7.3%) had t(1, 19) translocation, and 2 (3.6%) had t(9, 22) translocation. The initial white blood cells (p value

Details

Language :
English
ISSN :
17560500
Volume :
14
Issue :
1
Database :
OpenAIRE
Journal :
BMC Research Notes
Accession number :
edsair.doi.dedup.....f8b7d88e5026e8617cd0ea63dce907ed