Back to Search
Start Over
Ecological impact of isolated cognitive relapses in MS
- Publication Year :
- 2018
- Publisher :
- SAGE Publications Ltd, 2018.
-
Abstract
- Isolated cognitive relapses (ICRs) are transient deficits in cognitive performance that are the only presentation of a multiple sclerosis (MS) relapse. Here, we evaluated the impact of ICRs on cognitive difficulties in daily activities (assessed with the Multiple Sclerosis Neuropsychological Screening Questionnaire, Informant Version (MSNQ-I)) to characterize ICRs’ clinical relevance. We used 2-year-long retrospective data to compare 15 relapsing-remitting MS (RRMS) patients with ICRs with 57 RRMS patients presenting an asymptomatic gadolinium enhancing lesion (and no-ICRs). ICRs were associated not only with neuropsychological performance decline but also with an increase in the daily cognitive difficulties. These findings support the ecological relevance of ICRs.
- Subjects :
- Adult
Male
cognition
Activities of daily living
cognition, quality of life, Relapses, Neurology, Neurology (clinical)
animal diseases
Asymptomatic
03 medical and health sciences
Multiple Sclerosis, Relapsing-Remitting
0302 clinical medicine
Quality of life
Recurrence
medicine
Humans
Cognitive Dysfunction
Clinical significance
Longitudinal Studies
030212 general & internal medicine
Effects of sleep deprivation on cognitive performance
Retrospective Studies
Ecology
business.industry
Multiple sclerosis
Neuropsychology
virus diseases
Cognition
Middle Aged
medicine.disease
Magnetic Resonance Imaging
quality of life
Neurology
Female
Neurology (clinical)
medicine.symptom
business
030217 neurology & neurosurgery
Relapses
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....f849c12235d07e0765cb8bcdd06ca8cb