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The Increment of Short-term Variability of Repolarisation Determines the Severity of the Imminent Arrhythmic Outcome
- Source :
- Arrhythmia & Electrophysiology Review, Arrhythmia & Electrophysiology Review, Vol 8, Iss 3, Pp 166-172 (2019)
- Publication Year :
- 2019
- Publisher :
- Radcliffe Cardiology, 2019.
-
Abstract
- Ventricular remodelling can make the heart more susceptible to ventricular arrhythmias like torsades de pointes. Understanding the underlying mechanisms of initiation of ventricular arrhythmias and the determining factors for its severity has the potential to uncover new interventions. Beat-to-beat variation of repolarisation, quantified as short-term variability of repolarisation (STV), has been identified as an important factor contributing to arrhythmogenesis. This article provides an overview of experimental data about STV in relation to the initiation of torsades de pointes in a canine model of complete chronic atrioventricular block susceptible to torsades de pointes arrhythmias. Furthermore, it explores STV in relation to the severity of the arrhythmic outcome.
- Subjects :
- medicine.medical_specialty
Cardiomyopathy
Torsades de pointes
Physiology (medical)
Internal medicine
medicine
Diseases of the circulatory (Cardiovascular) system
Myocardial infarction
cardiovascular diseases
Stroke
business.industry
Short Term Variability
beat-to-beat variation of repolarisation
ventricular arrhythmias
Atrial fibrillation
medicine.disease
RC666-701
Heart failure
Cardiology
cardiovascular system
Clinical Arrhythmias
torsades de pointes
Cardiology and Cardiovascular Medicine
business
Atrioventricular block
Short-term variability of repolarisation
Subjects
Details
- Language :
- English
- ISSN :
- 20503377 and 20503369
- Volume :
- 8
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Arrhythmia & Electrophysiology Review
- Accession number :
- edsair.doi.dedup.....f8428634d693ff9275bd4d19b67bb37f