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Dot by dot: Analyzing the glycome using lectin microarrays
- Publication Year :
- 2013
-
Abstract
- The glycome, that is, the cohort of carbohydrates within a cell or tissue, plays a key part in diverse biological interactions involved in health and disease. Glycans are structurally complex and notoriously difficult to analyze. Lectin microarrays, a sensitive and high-throughput method for glycomic profiling, provide a global view of the glycome. In recent work, this technology has been successfully applied to a wide range of studies, from identification of glycan-based stem cell markers to the detection of pathogens and early diagnosis of disease. This review focuses on advances in the field of lectin microarrays.
- Subjects :
- Glycan
Glycosylation
Color
Computational biology
Stem cell marker
Biochemistry
Article
Analytical Chemistry
Glycomics
03 medical and health sciences
chemistry.chemical_compound
Polysaccharides
Lectins
Humans
030304 developmental biology
0303 health sciences
biology
030302 biochemistry & molecular biology
Lectin
Glycome
Molecular biology
3. Good health
chemistry
biology.protein
DNA microarray
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....f806ea8ed99345ff3f673b0b36f54477