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Animal and in vitro Models for the Study of Hair Follicles
- Source :
- Journal of Investigative Dermatology Symposium Proceedings. 8:39-45
- Publication Year :
- 2003
- Publisher :
- Elsevier BV, 2003.
-
Abstract
- Since the way in which the hair follicle functions is not well understood, many hair disorders are poorly controlled. A range of in vitro and in vivo models have therefore been developed to investigate the cell biological and biochemical mechanisms involved in the organization of this complex tissue. These range from cultures of a single cell type, such as those of the regulatory, mesenchyme-derived dermal papilla, through organ culture of isolated follicles to natural or genetically manipulated animal models. Each system has advantages and disadvantages for studying particular aspects of follicular function and some are potentially useful for the development of novel treatments for hair disorders.
- Subjects :
- Cell type
Pathology
medicine.medical_specialty
Dermatology
Biology
Organ culture
Mice
organ culture
030207 dermatology & venereal diseases
03 medical and health sciences
Organ Culture Techniques
0302 clinical medicine
In vivo
medicine
Animals
Humans
human
Molecular Biology
Cells, Cultured
mouse
030304 developmental biology
0303 health sciences
integumentary system
genetically engineered mice
Cell Biology
General Medicine
Hair follicle
Mice, Mutant Strains
In vitro
Cell biology
medicine.anatomical_structure
Dermal papillae
dermal papilla cells
Hair Disorder
Hair Follicle
Function (biology)
Hair
Biotechnology
Subjects
Details
- ISSN :
- 10870024
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of Investigative Dermatology Symposium Proceedings
- Accession number :
- edsair.doi.dedup.....f7a97165ad19762ccb3c95eec35e4497