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Crimean-Congo haemorrhagic fever virus in Kazakhstan (1948-2013)
- Source :
- International Journal of Infectious Diseases, Vol 38, Iss C, Pp 19-23 (2015)
- Publisher :
- Published by Elsevier Ltd.
-
Abstract
- Crimean-Congo haemorrhagic fever (CCHF) is a pathogenic and often fatal arboviral disease with a distribution spanning large areas of Africa, Europe and Asia. The causative agent is a negative-sense single-stranded RNA virus classified within the Nairovirus genus of the Bunyaviridae family.Cases of CCHF have been officially recorded in Kazakhstan since the disease was first officially reported in modern medicine. Serological surveillance of human and animal populations provide evidence that the virus was perpetually circulating in a local enzoonotic cycle involving mammals, ticks and humans in the southern regions of the country. Most cases of human disease were associated with agricultural professions such as farming, shepherding and fruit-picking; the typical route of infection was via tick-bite although several cases of contact transmission associated with caring for sick patients have been documented.In total, 704 confirmed human cases of CCHF have been registered in Kazakhstan from 1948-2013 with an overall case fatality rate of 14.8% for cases with a documented outcome.The southern regions of Kazakhstan should be considered endemic for CCHF with cases reported from these territories on an annual basis. Modern diagnostic technologies allow for rapid clinical diagnosis and for surveillance studies to monitor for potential expansion in known risk areas.
- Subjects :
- Microbiology (medical)
Modern medicine
Endemic Diseases
Disease
History, 21st Century
Virus
lcsh:Infectious and parasitic diseases
Serology
Ticks
Central Asia
Case fatality rate
CCHF
Animals
Humans
lcsh:RC109-216
Crimean-Congo haemorrhagic fever
Nairovirus
biology
Incidence
RNA virus
General Medicine
History, 20th Century
biology.organism_classification
Virology
Kazakhstan
Infectious Diseases
Geography
Hemorrhagic Fever Virus, Crimean-Congo
Hemorrhagic Fever, Crimean
Bunyaviridae
Subjects
Details
- Language :
- English
- ISSN :
- 12019712
- Database :
- OpenAIRE
- Journal :
- International Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....f792c4e63e3fd79b60fd9d0ae5162d25
- Full Text :
- https://doi.org/10.1016/j.ijid.2015.07.007