Back to Search
Start Over
Nanoparticle Therapy for Prostate Cancer: Overview and Perspectives
- Source :
- Current topics in medicinal chemistry. 19(1)
- Publication Year :
- 2018
-
Abstract
- Traditional prostate cancer therapy and especially chemotherapy has faced many challenges. Low accumulation levels, rapid clearance or drug resistance at the tumor site have been central to why the effect of chemotherapy drugs has declined. Applications of nanotechnology to biomedicine have enabled the development of nanoparticle therapeutic carriers suited for the delivery of chemotherapeutics in cancer therapy. This review describes the current nature of nanoparticle therapeutic carriers for prostate cancer. It describes typical nanocarriers commonly used for the delivery of chemotherapy or for imaging examination. Targeting strategies and related influencing factors are investigated to find ways of enhancing treatment effects of nanoparticles. The overall purpose of this review is to further understanding and to offer recommendations on the design and development of therapeutic nanoparticles for prostate cancer.
- Subjects :
- Oncology
medicine.medical_specialty
medicine.medical_treatment
Cancer therapy
Antineoplastic Agents
02 engineering and technology
Drug resistance
03 medical and health sciences
Prostate cancer
0302 clinical medicine
Drug Delivery Systems
Internal medicine
Neoplasms
Drug Discovery
medicine
Animals
Humans
Biomedicine
Cell Proliferation
Chemotherapy
Drug Carriers
business.industry
General Medicine
021001 nanoscience & nanotechnology
medicine.disease
Applications of nanotechnology
030220 oncology & carcinogenesis
Drug delivery
Nanoparticles
Nanocarriers
Drug Screening Assays, Antitumor
0210 nano-technology
business
Subjects
Details
- ISSN :
- 18734294
- Volume :
- 19
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Current topics in medicinal chemistry
- Accession number :
- edsair.doi.dedup.....f74493071e7ad36bbf0e9d755946f892