Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020

Authors :: Krista Kniss
Juan A. De La Cruz
Anton Chesnokov
Larisa V. Gubareva
Angiezel Merced-Morales
Jennifer Laplante
Kirsten St. George
David E. Wentworth
Rebecca Kondor
Teena Mohan
Ha T. Nguyen
Vasiliy P. Mishin
Patricia A. Blevins
Source :: Emerging Infectious Diseases, Vol 27, Iss 7, Pp 1953-1957 (2021), Emerging Infectious Diseases
Publication Year :: 2021
Publisher :: Centers for Disease Control and Prevention, 2021.
Abstract: Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.

Subjects :: Microbiology (medical)
Oseltamivir
Epidemiology
medicine.drug_class
viruses
030231 tropical medicine
Hemagglutinin (influenza)
Neuraminidase
Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020
Infectious and parasitic diseases
RC109-216
Antiviral Agents
Antigenic drift
Virus
03 medical and health sciences
chemistry.chemical_compound
Viral Proteins
0302 clinical medicine
Antibiotic resistance
Influenza A Virus, H1N1 Subtype
Drug Resistance, Viral
Influenza, Human
medicine
Humans
030212 general & internal medicine
antimicrobial resistance
antigenic drift
drug resistance
biology
Neuraminidase inhibitor
neuraminidase inhibitor
Dispatch
transmission
virus diseases
Subclade
Virology
Texas
United States
Infectious Diseases
Hemagglutinins
chemistry
biology.protein
Medicine
influenza
influenza A(H1N1)

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