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Approach to patients with pseudo-Cushing’s states
- Source :
- Endocrine Connections, Endocrine Connections, Vol 9, Iss 1, Pp R1-R13 (2020)
- Publication Year :
- 2020
- Publisher :
- BioScientifica Ltd., 2020.
-
Abstract
- The distinction between pseudo-Cushing’s states (PCS) and Cushing’s syndrome (CS) poses a significant clinical challenge even for expert endocrinologists. A patient’s clinical history can sometimes help to distinguish between them (as in the case of alcoholic individuals), but the overlap in clinical and laboratory findings makes it difficult to arrive at a definitive diagnosis. We aim to describe the most common situations that can give rise to a condition resembling overt endogenous hypercortisolism and try to answer questions that physicians often face in clinical practice. It is important to know the relative prevalence of these different situations, bearing in mind that most of the conditions generating PCS are relatively common (such as metabolic syndrome and polycystic ovary syndrome), while CS is rare in the general population. Physicians should consider CS in the presence of additional features. Appropriate treatment of underlying conditions is essential as it can reverse the hormonal abnormalities associated with PCS. Close surveillance and a thorough assessment of a patient’s hormone status will ultimately orient the diagnosis and treatment options over time.
- Subjects :
- medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
Population
030209 endocrinology & metabolism
Review
Diabete
lcsh:Diseases of the endocrine glands. Clinical endocrinology
03 medical and health sciences
0302 clinical medicine
Endocrinology
Clinical history
Internal Medicine
medicine
PCOS
030212 general & internal medicine
Obesity
Intensive care medicine
education
education.field_of_study
lcsh:RC648-665
business.industry
Pseudo-Cushing’s
Diabetes
Eating disorder
Treatment options
Polycystic ovary
Clinical Practice
Neuropsychiatric disorder
Alcoholism
Eating disorders
Neuropsychiatric disorders
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Endocrine Connections, Endocrine Connections, Vol 9, Iss 1, Pp R1-R13 (2020)
- Accession number :
- edsair.doi.dedup.....f715cb4a216432d0b6e9a4a649af145f