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The tandem intermolecular hydroalkoxylation/claisen rearrangement

Authors :
John M. Ketcham
Aaron Aponick
Berenger Biannic
Source :
Chem. Commun.. 49:4157-4159
Publication Year :
2013
Publisher :
Royal Society of Chemistry (RSC), 2013.

Abstract

The Au(I)-catalyzed intermolecular hydroalkoxylation of alkynes with allylic alcohols to provide allyl vinyl ethers that subsequently undergo Claisen rearrangement is reported. This new cascade reaction strategy facilitates the direct formation of γ,δ-unsaturated ketones from simple starting materials in a single step.

Details

ISSN :
1364548X and 13597345
Volume :
49
Database :
OpenAIRE
Journal :
Chem. Commun.
Accession number :
edsair.doi.dedup.....f6e33a481e4699181cc20f5928fdc0a8
Full Text :
https://doi.org/10.1039/c2cc37166a