Back to Search
Start Over
Stable recombination hotspots in birds
- Source :
- Science. 350(6263)
- Publication Year :
- 2015
-
Abstract
- Recombination: The birds and the yeast Apes and mice have a specific gene, PRDM9 , that is associated with genomic regions with high rates of recombination, called hotspots. In species with PRDM9 , hotspots move rapidly within the genome, varying among populations and closely related species (see the Perspective by Lichten). To investigate recombination hotspots in species lacking PRDM9 , Singhal et al. examined bird genomes, which lack a PRDM9 gene. They looked closely at the genomes of finch species and found that recombination was localized to the promoter regions of genes and highly conserved over millions of years. Similarly, Lam and Keeney examined recombination localization within yeast, which also lacks PRDM9 . They found a similar more-or-less fixed pattern of hotspots. Thus, recombination in species lacking a PRDM9 gene shows similar patterns of hotspot localization and evolution. Science , this issue p. 913 , p. 928 ; see also p. 932
- Subjects :
- 0106 biological sciences
Population
010603 evolutionary biology
01 natural sciences
Article
Evolution, Molecular
03 medical and health sciences
Species Specificity
biology.animal
Animals
education
Zebra finch
PRDM9
030304 developmental biology
Recombination, Genetic
Genetics
0303 health sciences
education.field_of_study
Genome
Multidisciplinary
biology
Chromosome Mapping
Vertebrate
biology.organism_classification
Repressor Proteins
Gene Expression Regulation
Evolutionary biology
Finches
Poephila acuticauda
Homologous recombination
Recombination
Taeniopygia
Subjects
Details
- ISSN :
- 10959203 and 00368075
- Volume :
- 350
- Issue :
- 6263
- Database :
- OpenAIRE
- Journal :
- Science
- Accession number :
- edsair.doi.dedup.....f6d251522a42bf5b051c5b4d79e06a7e