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Hyper IgE Syndrome and Renal Cell Carcinoma
- Source :
- Case Reports in Urology, Case Reports in Urology, Vol 2017 (2017)
- Publication Year :
- 2017
- Publisher :
- Hindawi Limited, 2017.
-
Abstract
- Hyper IgE Syndrome (HIES) is an immunodeficiency disorder characterized by increased serum levels of IgE, eczema, and recurrent cutaneous and pulmonary infections. In this report, we present, to our knowledge, the first documented case of renal cell carcinoma (RCC) found in a patient with HIES. The patient received infectious disease clearance prior to obtaining a partial nephrectomy which revealed clear cell histology. Both HIES and RCC have an immunological basis for their pathophysiology and may involve common pathways. Further studies may provide insight into any possible link and clinicians should be mindful of immunocompromised patients who present with risk factors for genitourinary malignancy.
- Subjects :
- 0301 basic medicine
biology
Genitourinary system
business.industry
medicine.medical_treatment
Case Report
General Medicine
lcsh:Diseases of the genitourinary system. Urology
lcsh:RC870-923
Immunoglobulin E
medicine.disease
Malignancy
Nephrectomy
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Renal cell carcinoma
Job Syndrome
030220 oncology & carcinogenesis
Immunology
biology.protein
medicine
Carcinoma
business
Clear cell
Subjects
Details
- ISSN :
- 20906978 and 2090696X
- Volume :
- 2017
- Database :
- OpenAIRE
- Journal :
- Case Reports in Urology
- Accession number :
- edsair.doi.dedup.....f6d037d3a845db9e4d5b47468be1d22e