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Review of seasonal influenza in Canada: Burden of disease and the cost-effectiveness of quadrivalent inactivated influenza vaccines
- Source :
- Human Vaccines & Immunotherapeutics
- Publication Year :
- 2017
- Publisher :
- Informa UK Limited, 2017.
-
Abstract
- In the 2015/16 influenza season, the Canadian National Advisory Committee on Immunization (NACI) recommended vaccination with quadrivalent inactivated influenza vaccine (QIV) for infants aged 6–23 months and trivalent inactivated influenza vaccines (TIVs) or QIVs in adults. The objective of this review (GSK study identifier: HO-13-14054) is to examine the epidemiology and disease burden of influenza in Canada and the economic benefits of vaccination. To inform this review, we performed a systematic literature search of relevant Canadian literature and National surveillance data. Influenza B viruses from phylogenetically-distinct lineages (B/Yamagata and B/Victoria) co-circulate in Canada, and are an important cause of influenza complications. Modeling studies, including those postdating the search suggest that switching from TIV to QIV in Canada reduces the burden of influenza and would likely be cost-effective. However, more robust real-world outcomes data is required to inform health policy decision makers on appropriate influenza vaccination strategies for Canada.
- Subjects :
- Quadrivalent Inactivated Influenza Vaccine
Canada
Victoria
Influenza vaccine
Cost effectiveness
Cost-Benefit Analysis
Immunology
costs
Review
burden
Seasonal influenza
03 medical and health sciences
0302 clinical medicine
Cost of Illness
Influenza, Human
Humans
Immunology and Allergy
Medicine
Live attenuated influenza vaccine
quadrivalent
030212 general & internal medicine
Pharmacology
Models, Statistical
030505 public health
business.industry
Vaccination
virus diseases
Virology
lineage-mismatch
Vaccines, Inactivated
Immunization
Influenza Vaccines
Human mortality from H5N1
epidemiology
influenza vaccine
influenza
0305 other medical science
business
hospitalization
Subjects
Details
- ISSN :
- 2164554X and 21645515
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Human Vaccines & Immunotherapeutics
- Accession number :
- edsair.doi.dedup.....f680102a9aedc8c0a8bcbd6258428c3c