Back to Search Start Over

TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response

Authors :
Taewoo, Kim
Jessica, Johnston
Sonia, Castillo-Lluva
Francisco J, Cimas
Stephen, Hamby
Santiago, Gonzalez-Moreno
Pedro, Villarejo-Campos
Alison H, Goodall
Guillermo, Velasco
Alberto, Ocana
Munitta, Muthana
Endre, Kiss-Toth
Source :
Theranostics. 12(8)
Publication Year :
2022

Abstract

Molecular mechanisms that regulate tumor-associated macrophage (TAM) phenotype and function are incompletely understood. The pseudokinase TRIB1 has been reported as a regulator of macrophage phenotypes, both in mouse and human systems.

Details

ISSN :
18387640
Volume :
12
Issue :
8
Database :
OpenAIRE
Journal :
Theranostics
Accession number :
edsair.doi.dedup.....f67ea301d522e9e5e1fb750b818f83e6