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Prevention of Capsular Contracture Using Leukotriene Antagonists
- Source :
- Plastic and Reconstructive Surgery. 136:592e-596e
- Publication Year :
- 2015
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2015.
-
Abstract
- Capsular contracture is a common occurrence in plastic surgery, with a prevalence varying from 0.5 percent up to 30 percent. Although the standard treatment is capsulectomy, alternative treatments have been studied, such as the use of leukotriene inhibitors. These drugs have recently been evaluated in the prophylaxis of contracture. The authors aimed to assess the efficacy of montelukast (Singulair) in the prevention of capsular contracture in patients undergoing mammaplasty with textured silicone prostheses.The authors followed 82 patients (164 breasts) for a minimum of 2 years. Of these, 37 were administered montelukast.The number of affected patients and the severity were higher among the 45 patients who did not use montelukast.The prophylactic use of Singulair was, in this sample, shown to be effective in helping to reduce the incidence of capsular contracture.Therapeutic, III.
- Subjects :
- Adult
Cyclopropanes
medicine.medical_specialty
Adolescent
Breast Implants
Mammaplasty
Treatment outcome
Acetates
Sulfides
Risk Assessment
Cohort Studies
Young Adult
Primary prevention
Implant Capsular Contracture
medicine
Humans
Retrospective Studies
Leukotriene
Leukotriene Antagonists
business.industry
Standard treatment
Follow up studies
Capsular contracture
Middle Aged
Surgery
Primary Prevention
Plastic surgery
Logistic Models
Treatment Outcome
Multivariate Analysis
Quinolines
Female
business
Brazil
Follow-Up Studies
Subjects
Details
- ISSN :
- 00321052
- Volume :
- 136
- Database :
- OpenAIRE
- Journal :
- Plastic and Reconstructive Surgery
- Accession number :
- edsair.doi.dedup.....f67a5426f9177aeb6617dc87c60de354