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Trends in Prescriptions for Non-opioid Pain Medications Among U.S. Adults With Moderate or Severe Pain, 2014-2018
- Source :
- The journal of pain, vol 23, iss 7, J Pain
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- As opioid prescribing has declined, it is unclear how the landscape of prescription pain treatment across the U.S. has changed. We used nationally-representative data from the Medical Expenditure Health Survey, 2014 to 2018 to examine trends in prescriptions for opioid and non-opioid pain medications, including acetaminophen, non-steroidal anti-inflammatory drugs, gabapentinoids, and antidepressants among U.S. adults with self-reported pain. Overall, from 2014 to 2018, the percentage of participants receiving a prescription for opioids declined, (38.8% vs 32.8%), remained stable for non-steroidal anti-inflammatory drugs (26.8% vs 27.7%), and increased for acetaminophen (1.6% vs 2.3%), antidepressants (9.6% vs 12.0%) and gabapentinoids (13.2% vs 19.0%). In this period, the adjusted odds of receiving an opioid prescription decreased (aOR=.93, 95% CI=.90-.96), while the adjusted odds of receiving antidepressant, gabapentinoid and acetaminophen prescriptions increased (antidepressants: aOR=1.08, 95% CI=1.03-1.13 gabapentinoids: aOR=1.11, 95% CI=1.06-1.17; acetaminophen: aOR=1.10, 95% CI: 1.02-1.20). Secondary analyses stratifiying within the 2014 to 2016 and 2016 to 2018 periods revealed particular increases in prescriptions for gabapentinoids (aOR=1.13, 95% CI=1.05-1.21) and antidepressants (aOR=1.23, 95% CI=1.12-1.35) since 2016. PERSPECTIVE: These data demonstrate that physicians are increasingly turning to CDC-recommended non-opioid medications for pain management, particularly antidepressants and gabapentinoids. However, evidence for these medications' efficacy in treating numerous common pain conditions, including low back pain, remains limited.
- Subjects :
- Adult
NSAIDs
gabapentin
Anti-Inflammatory Agents
Pain
Opioid
Practice Patterns
Drug Prescriptions
Medical and Health Sciences
Article
Anesthesiology
Humans
Practice Patterns, Physicians'
Acetaminophen
acetaminophen
Analgesics
Physicians'
Pain Research
Psychology and Cognitive Sciences
opioids
Evaluation of treatments and therapeutic interventions
Antidepressive Agents
Analgesics, Opioid
Prescriptions
Good Health and Well Being
Anesthesiology and Pain Medicine
Neurology
antidepressants
6.1 Pharmaceuticals
 
epidemiology
pregabalin
Neurology (clinical)
Chronic Pain
Low Back Pain
Subjects
Details
- ISSN :
- 15265900
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- The Journal of Pain
- Accession number :
- edsair.doi.dedup.....f62180e1ffe4b6c80bb07e0d26412c38