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Hyperinsulinemia increases the risk of gestational hypertension
- Source :
- International Journal of Gynecology & Obstetrics. 55:141-145
- Publication Year :
- 1996
- Publisher :
- Wiley, 1996.
-
Abstract
- To determine whether hyperinsulinemia is related to gestational hypertension.We measured the arterial blood pressure and the level of immunoreactive insulin (IRI) during a 75 g oral glucose tolerance test in a total of 84 pregnant women. Hyperinsulinemia was defined as a fasting IRI levelor = 9 IU/l, while gestational hypertension was defined as arterial blood pressureor = 140/90 mmHg.The incidence of gestational hypertension was higher in the hyperinsulinemic group (n = 29) than in the control group (n = 55) (24.1% vs. 7.3%, respectively P0.05). After controlling for maternal age, parity, pre-pregnancy body mass index and the gestational age at the time of oral glucose tolerance test (OGTT), using a multiple regression model, the relative risk of developing gestational hypertension for a fasting insulin level was 1.19 (95% C.I., 1.03-1.38).Pregnant women with hyperinsulinemia are at increased risk of developing gestational hypertension.
- Subjects :
- Adult
Gestational hypertension
medicine.medical_specialty
medicine.medical_treatment
Pregnancy Complications, Cardiovascular
Pregnancy
Hyperinsulinism
Internal medicine
Hyperinsulinemia
medicine
Humans
Prospective Studies
Pancreatic hormone
Glucose tolerance test
medicine.diagnostic_test
business.industry
Insulin
Obstetrics and Gynecology
General Medicine
Glucose Tolerance Test
medicine.disease
Pregnancy Complications
Blood pressure
Endocrinology
Pregnancy Trimester, Second
Hypertension
Multivariate Analysis
Gestation
Female
business
Subjects
Details
- ISSN :
- 00207292
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- International Journal of Gynecology & Obstetrics
- Accession number :
- edsair.doi.dedup.....f602c7fc2370c87544bea1b27a6b4b17