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New production cross sections for the theranostic radionuclide 67 Cu
- Source :
- Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Elsevier, 2018, 415, pp.41-47. ⟨10.1016/j.nimb.2017.10.022⟩
- Publication Year :
- 2018
- Publisher :
- HAL CCSD, 2018.
-
Abstract
- The cross sections of the 68Zn(p,2p)67Cu, 68Zn(p,2n)67Ga and 68Zn(p,3n)66Ga reactions were measured at the ARRONAX facility by using the 70 MeV cyclotron, with particular attention to the production of the theranostic radionuclide 67Cu. Enriched 68Zn material was electroplated on silver backing and exposed to a low-intensity proton beam by using the stacked-foils target method. Since 67Cu and 67Ga radionuclides have similar half-lives and same γ-lines (they both decay to 67Zn), a radiochemical process aimed at Cu/Ga separation was mandatory to avoid interferences in γ-spectrometry measurements. A simple chemical procedure having a high separation efficiency (>99%) was developed and monitored during each foil processing, thanks to the tracer isotopes 61Cu and 66Ga. Nuclear cross sections were measured in the energy range 35–70 MeV by using reference reactions recommended by the International Atomic Energy Agency (IAEA) to monitor beam flux. In comparison with literature data a general good agreement on the trend of the nuclear reactions was noted, especially with latest measurements, but slightly lower values were obtained in case of 67Cu. Experimental results of the 68Zn(p,2p)67Cu, 68Zn(p,2n)67Ga and 68Zn(p,3n)66Ga reactions were also compared with the theoretical values estimated by using the software TALYS. The production yield of the theranostic radionuclide 67Cu was estimated considering the results obtained in this work.
- Subjects :
- Nuclear reaction
[PHYS]Physics [physics]
Nuclear and High Energy Physics
Radionuclide
Proton
Isotope
Chemistry
Radiochemistry
Cyclotron
[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]
010403 inorganic & nuclear chemistry
7. Clean energy
01 natural sciences
030218 nuclear medicine & medical imaging
0104 chemical sciences
law.invention
03 medical and health sciences
0302 clinical medicine
law
TRACER
Yield (chemistry)
Instrumentation
Beam (structure)
ComputingMilieux_MISCELLANEOUS
Subjects
Details
- Language :
- English
- ISSN :
- 0168583X
- Database :
- OpenAIRE
- Journal :
- Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Elsevier, 2018, 415, pp.41-47. ⟨10.1016/j.nimb.2017.10.022⟩
- Accession number :
- edsair.doi.dedup.....f5e405f6f32eb3a86c338aa8ef7112c7