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Non-Elective Paraesophageal Hernia Repair Portends Worse Outcomes in Comparable Patients: a Propensity-Adjusted Analysis
- Source :
- Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 21(1)
- Publication Year :
- 2016
-
Abstract
- Patients undergoing non-elective paraesophageal hernia repair (PEHR) have worse perioperative outcomes. Because they are usually older and sicker, however, these patients may be more prone to adverse events, independent of surgical urgency. Our study aimed to determine whether non-elective PEHR is associated with differential postoperative outcome compared to elective repair, using propensity-score weighting.We abstracted data for patients undergoing PEHR (n = 924; non-elective n = 171 (19 %); 1997-2010). Using boosted regression, we generated a propensity-weighted dataset. Odds of 30-day/in-hospital mortality and major complications after non-elective surgery were determined.Patients undergoing non-elective repair were significantly older, had more adverse prognostic factors, and significantly more major complications (38 versus 18 %; p 0.001) and death (8 versus 1 %; p 0.001). After propensity weighting, median absolute percentage bias across 28 propensity-score variables improved from 19 % (significant imbalance) to 5.6 % (well-balanced). After adjusting propensity-weighted data for age and comorbidity score, odds of major complications were still nearly two times greater (OR 1.67, CI 1.07-2.61) and mortality nearly three times greater (OR 2.74, CI 0.93-8.1) than for elective repair.Even after balancing significant differences in baseline characteristics, non-elective PEHR was associated with worse outcomes than elective repair. Symptomatic patients should be referred for elective repair by experienced surgeons.
- Subjects :
- Male
medicine.medical_specialty
Paraesophageal
genetic structures
health care facilities, manpower, and services
medicine.medical_treatment
Comorbidity
030230 surgery
Article
Hiatal hernia
03 medical and health sciences
0302 clinical medicine
Postoperative Complications
medicine
Humans
Hospital Mortality
Propensity Score
health care economics and organizations
Herniorrhaphy
Aged
Retrospective Studies
Aged, 80 and over
business.industry
General surgery
Gastroenterology
Age Factors
Retrospective cohort study
Perioperative
Middle Aged
medicine.disease
Hernia repair
Surgery
Hernia, Hiatal
Treatment Outcome
030220 oncology & carcinogenesis
Propensity score matching
Female
business
Elective Surgical Procedure
Subjects
Details
- ISSN :
- 18734626
- Volume :
- 21
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
- Accession number :
- edsair.doi.dedup.....f5db5a3d252f911715494aebd8dd03d3