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Active and passive smoking and the risk of breast cancer in women aged 36-45 years: a population based case-control study in the UK
- Source :
- British Journal of Cancer
- Publication Year :
- 2016
-
Abstract
- Active smoking has little or no effect on breast cancer risk but some investigators have suggested that passive smoking and its interaction with active smoking may be associated with an increased risk. In a population based case-control study of breast cancer in women aged 36-45 years at diagnosis, information on active smoking, passive smoking in the home, and other factors, was collected at interview from 639 cases and 640 controls. Women were categorised jointly by their active and passive smoking exposure. Among never smoking controls, women who also reported no passive smoking exposure were significantly more likely to be nulliparous and to be recent users of oral contraceptives. Among those never exposed to passive smoking, there was no significant association between active smoking and breast cancer, relative risk (RR) of 1.12 (95% confidence interval (CI) 0.72-1.73) for past smokers and RR of 1.19 (95% CI 0.72-1.95) for current smokers, nor was there an association with age started, duration or intensity of active smoking. Compared with women who were never active nor passive smokers, there was no significant association between passive smoking in the home and breast cancer risk in never smokers, RR of 0.89 (95% CI 0.64-1.25), in past smokers, RR of 1.09 (95% CI 0.75-1.56), or in current smokers, RR of 0.93 (95% CI 0.67-1.30). There was no trend with increasing duration of passive smoking and there was no heterogeneity among any of the subgroups examined. In this study, there was no evidence of an association between either active smoking or passive smoking in the home and risk of breast cancer.
- Subjects :
- Adult
Cancer Research
medicine.medical_specialty
Passive smoking
Epidemiology
case-control study
Breast Neoplasms
Population based
medicine.disease_cause
breast cancer
Breast cancer
Internal medicine
medicine
Humans
Risk factor
Gynecology
passive smoking
business.industry
Smoking
Case-control study
Middle Aged
medicine.disease
United Kingdom
Confidence interval
Oncology
Case-Control Studies
Population Surveillance
Relative risk
Female
Tobacco Smoke Pollution
business
Subjects
Details
- Language :
- English
- ISSN :
- 00070920
- Database :
- OpenAIRE
- Journal :
- British Journal of Cancer
- Accession number :
- edsair.doi.dedup.....f5da7f0cd6958507cb1bc9854b71ff01