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Mechanisms of carbapenem resistance among a collection of Enterobacteriaceae clinical isolates in a Texas city
- Source :
- Diagnostic microbiology and infectious disease. 66(4)
- Publication Year :
- 2009
-
Abstract
- Fourteen Enterobacteriaceae isolates with ertapenem MIC2 mg/mL were analyzed to identify mechanisms of resistance. All isolates produced extended-spectrum beta-lactamase or AmpC beta-lactamase with variable, but decreased, expression of outer membrane proteins. One Enterobacter cloacae produced derepressed AmpC beta-lactamase, 1 Escherichia coli expressed plasmid-mediated AmpC beta-lactamase, and 1 E. cloacae produced a carbapenemase.
- Subjects :
- Microbiology (medical)
Ertapenem
Carbapenem
medicine.medical_treatment
Drug resistance
Microbial Sensitivity Tests
medicine.disease_cause
beta-Lactams
beta-Lactam Resistance
beta-Lactamases
Microbiology
chemistry.chemical_compound
Bacterial Proteins
Enterobacteriaceae
polycyclic compounds
medicine
Humans
Escherichia coli
biology
Enterobacteriaceae Infections
General Medicine
biochemical phenomena, metabolism, and nutrition
biology.organism_classification
Virology
Texas
Anti-Bacterial Agents
Infectious Diseases
chemistry
Beta-lactamase
bacteria
Enterobacter cloacae
Bacteria
medicine.drug
Bacterial Outer Membrane Proteins
Plasmids
Subjects
Details
- ISSN :
- 18790070
- Volume :
- 66
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Diagnostic microbiology and infectious disease
- Accession number :
- edsair.doi.dedup.....f5ca03a6ddcbf1abebaa4f4a2d3da50f