The Wittig reaction with 2-deoxysugars: the role of triphenyl and trialkyltin halides

Authors :: Concetta Imperatore
Ernesto Fattorusso
Alfonso Mangoni
Valeria Costantino
Costantino, Valeria
Fattorusso, Ernesto
Imperatore, Concetta
Mangoni, Alfonso
Source :: Tetrahedron Letters. 42:8185-8187
Publication Year :: 2001
Publisher :: Elsevier BV, 2001.
Abstract: The application of the Wittig reaction to prepare chain-extended polyols starting from protected 2-deoxysugars has been investigated. The standard conditions cause alcohol elimination from the deoxysugar, leading to a diene. Triphenyl and tributyltin halides have been found to prevent alcohol elimination, so that the expected alkene is produced.

Subjects :: chemistry.chemical_classification
chemistry.chemical_compound
Diene
Chemistry
Alkene
Organic Chemistry
Drug Discovery
Wittig reaction
Tributyltin
Halide
Organic chemistry
Alcohol
Biochemistry

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