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Exercise for methamphetamine dependence: rationale, design, and methodology
- Source :
- Contemporary clinical trials, vol 37, iss 1, Mooney, LJ; Cooper, C; London, ED; Chudzynski, J; Dolezal, B; Dickerson, D; et al.(2014). Exercise for methamphetamine dependence: Rationale, design, and methodology. Contemporary Clinical Trials, 37(1), 139-147. doi: 10.1016/j.cct.2013.11.010. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5228n7p1
- Publication Year :
- 2014
- Publisher :
- eScholarship, University of California, 2014.
-
Abstract
- Background: Effective pharmacotherapies to treat methamphetamine (MA) dependence have not been identified, and behavioral therapies are marginally effective. Based on behavioral studies demonstrating the potential efficacy of aerobic exercise for improving depressive symptoms, anxiety, cognitive deficits, and substance use outcomes, the study described here is examining exercise as a potential treatment for MA-dependent individuals. Methods: This study is randomizing 150 participants with MA dependence at a residential treatment facility for addictive disorders to receive either a thrice-weekly structured aerobic and resistance exercise intervention or a health education condition. Recruitment commenced in March, 2010. Enrollment and follow-up phases are ongoing, and recruitment is exceeding targeted enrollment rates. Conclusions: Seeking evidence for a possibly effective adjunct to traditional behavioral approaches for treatment of MA dependence, this study is assessing the ability of an 8-week aerobic and resistance exercise protocol to reduce relapse to MA use during a 12-week follow-up period after discharge from residential-based treatment. The study also is evaluating improvements in health and functional outcomes during and after the protocol. This paper describes the design and methods of the study. © 2013 Elsevier Inc.
- Subjects :
- Male
Medical and Health Sciences
Residential Facilities
Methamphetamine
Drug Abuse
Pharmacology (medical)
General Clinical Medicine
Substance Abuse
Cognition
General Medicine
Middle Aged
Exercise Therapy
Mental Health
Anxiety
Female
Substance Abuse Treatment Centers
Public Health
medicine.symptom
medicine.drug
Adult
medicine.medical_specialty
Drug Abuse (NIDA Only)
Adolescent
Amphetamine-Related Disorders
Clinical Trials and Supportive Activities
Outcomes
Article
Young Adult
Methamphetamine dependence
Clinical Research
Behavioral study
Behavioral and Social Science
medicine
Aerobic exercise
Humans
Psychiatry
Exercise
Depressive symptoms
Treatment intervention
business.industry
Prevention
Resistance Training
Aerobic
Brain Disorders
Substance use
business
Mind and Body
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Contemporary clinical trials, vol 37, iss 1, Mooney, LJ; Cooper, C; London, ED; Chudzynski, J; Dolezal, B; Dickerson, D; et al.(2014). Exercise for methamphetamine dependence: Rationale, design, and methodology. Contemporary Clinical Trials, 37(1), 139-147. doi: 10.1016/j.cct.2013.11.010. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5228n7p1
- Accession number :
- edsair.doi.dedup.....f5694f7bf2458f220373e7d643697727