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Constraining the Teratogenicity of Pesticide Pollution by a Synthetic Nanoreceptor
- Source :
- Chemistry - An Asian Journal. 13:41-45
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- The teratogenicity of the pesticide nereistoxin (NTX) and its derivative thiocyclam (THI) towards aquatic life was dramatically constrained by a synthetic nanoreceptor, cucurbit[7]uril, through selective encapsulation of the pesticides (KCB[7]-NTX of 3.24(±0.31)×106 m-1 and KCB[7]-THI of 7.46(±0.10)×105 m-1 ), as evidenced by the rate of hatchability, morphology development, and tyrosinase activity of zebrafish larvae incubated with the pesticides (3-300 μm) in the absence and in the presence of 300 μm cucurbit[7]uril, demonstrating the significant potential of the nanoreceptor in managing ecological pollution of these pesticides.
- Subjects :
- Bridged-Ring Compounds
0301 basic medicine
Pollution
media_common.quotation_subject
010501 environmental sciences
Pesticide pollution
01 natural sciences
Biochemistry
Heterocyclic Compounds, 1-Ring
Structure-Activity Relationship
03 medical and health sciences
Zebrafish larvae
Animals
Tyrosinase activity
Zebrafish
0105 earth and related environmental sciences
media_common
Dose-Response Relationship, Drug
Molecular Structure
Chemistry
Organic Chemistry
Imidazoles
General Chemistry
Pesticide
Teratogens
030104 developmental biology
Larva
Environmental chemistry
Thiocyclam
Marine Toxins
Water Pollutants, Chemical
Subjects
Details
- ISSN :
- 18614728
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Chemistry - An Asian Journal
- Accession number :
- edsair.doi.dedup.....f5559569eadb0c911e6a5132d4744697