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Selective inhibition of an apicoplastic Aminoacyl-tRNA synthetase from Plasmodium falciparum
- Source :
- Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, ChemBioChem; Vol 14
- Publication Year :
- 2013
- Publisher :
- Wiley-VCH Verlag, 2013.
-
Abstract
- Submitted by Patrícia Correia (patriciacorreia@ua.pt) on 2018-10-24T13:51:28Z No. of bitstreams: 1 Hoen et al. - 2013 - Selective Inhibition of an Apicoplastic Aminoacyl-.pdf: 1389669 bytes, checksum: e04a635c3fdbfad5ec1ec22ceda6d79a (MD5) Approved for entry into archive by Patrícia Correia (patriciacorreia@ua.pt) on 2018-10-24T13:51:46Z (GMT) No. of bitstreams: 1 Hoen et al. - 2013 - Selective Inhibition of an Apicoplastic Aminoacyl-.pdf: 1389669 bytes, checksum: e04a635c3fdbfad5ec1ec22ceda6d79a (MD5) Made available in DSpace on 2018-10-24T13:51:46Z (GMT). No. of bitstreams: 1 Hoen et al. - 2013 - Selective Inhibition of an Apicoplastic Aminoacyl-.pdf: 1389669 bytes, checksum: e04a635c3fdbfad5ec1ec22ceda6d79a (MD5) Previous issue date: 2013 This work was supported by the EU FP7 grant HEALTH-F3-2009223024–Mephitis, and by grants BIO2009-09776 (to L.R.d.P.) and CTQ2008-00177 and SAF2011-30508-C02-01 (to M.R.) from the Spanish Ministry of Education and Science. E.M.N. is supported by a La Caixa/IRB International Ph.D. Program Fellowship. R.H., A.L., L.C., and N.C. were supported by the EU FP7 project grant. published
- Subjects :
- Drug
Models, Molecular
Erythrocytes
media_common.quotation_subject
Plasmodium falciparum
Molecular modeling
Combinatorial chemistry
Selective inhibition
Biochemistry
Plasmodium
Drug design
Amino Acyl-tRNA Synthetases
03 medical and health sciences
chemistry.chemical_compound
Antimalarials
Aminoacyl-tRNA synthetases
parasitic diseases
Humans
Available drugs
Malaria, Falciparum
Molecular Biology
030304 developmental biology
media_common
chemistry.chemical_classification
0303 health sciences
biology
030306 microbiology
Aminoacyl tRNA synthetase
Organic Chemistry
Enzyme inhibitors
biology.organism_classification
Adenosine Monophosphate
Malaria
Enzyme
chemistry
Drug Design
Molecular Medicine
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP, ChemBioChem; Vol 14
- Accession number :
- edsair.doi.dedup.....f51fbe930450c8305cceaefeff327db8