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Does epithelioid angiomyolipoma have poorer prognosis, compared with classic angiomyolipoma?
- Source :
- Investigative and Clinical Urology, Vol 59, Iss 6, Pp 357-362 (2018), Investigative and Clinical Urology
- Publication Year :
- 2018
- Publisher :
- Korean Urological Association, 2018.
-
Abstract
- Purpose: Classic angiomyolipoma (AML) is common benign kidney tumor. However, some studies have claimed that epithelioid angiomyolipoma (EAML) has malignant potential. We compared the patient characteristics and prognosis of EAML and classic AML to demonstrate predicting factors and poorer prognosis of EAML. Materials and Methods: The medical records of 231 patients who were diagnosed with EAML (n=27, 11.7%) or classic AML (n=204, 88.3%), were reviewed. All patients underwent computed tomography (CT) scans before operation or needle biopsy. We assessed the age, sex, tumor size, body mass index, comorbidities, and Hounsfield unit (HU) according to each CT phase. We defined the unfavorable group as patients with recurrence, metastasis and death due to tumor progression. Logistic regression analysis was used to predict EAML. Results: EAML patients were younger (41.2 years vs. 49.1 years, p=0.001), predominantly male (55.6% vs. 28.4%, p=0.005), and had a larger tumor (7.5 cm vs. 4.2 cm, p
- Subjects :
- Adult
Male
medicine.medical_specialty
Lung Neoplasms
Angiomyolipoma
Urological Oncology
Urology
030232 urology & nephrology
Malignancy
lcsh:RC870-923
Metastasis
03 medical and health sciences
Sex Factors
0302 clinical medicine
Hounsfield scale
Humans
Medicine
Retrospective Studies
business.industry
Medical record
Epithelioid Cells
Age Factors
Odds ratio
Middle Aged
medicine.disease
Prognosis
lcsh:Diseases of the genitourinary system. Urology
Kidney Neoplasms
Tumor Burden
Cell Transformation, Neoplastic
Tumor progression
Lymphatic Metastasis
030220 oncology & carcinogenesis
Original Article
Female
Radiology
Tomography, X-Ray Computed
business
Body mass index
Subjects
Details
- Language :
- English
- ISSN :
- 24660493
- Volume :
- 59
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Investigative and Clinical Urology
- Accession number :
- edsair.doi.dedup.....f51472a217c88675f81bde3a00b3418d