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Where, in antiviral defense, does IFIT1 fit?

Authors :
Veit Hornung
Andrea Ablasser
Source :
Nature Immunology. 12:588-590
Publication Year :
2011
Publisher :
Springer Science and Business Media LLC, 2011.

Abstract

New data show that the interferon-induced gene product IFIT1 is a sensor for 5′-triphosphorylated RNA of viral origin and that it functions within a larger IFIT complex to inhibit viral replication.

Details

ISSN :
15292916 and 15292908
Volume :
12
Database :
OpenAIRE
Journal :
Nature Immunology
Accession number :
edsair.doi.dedup.....f4e5f0750a462b2272f7f52cb91147c1
Full Text :
https://doi.org/10.1038/ni.2061