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The AAA+ superfamily of functionally diverse proteins
- Source :
- Genome Biology
- Publication Year :
- 2008
- Publisher :
- Springer Science and Business Media LLC, 2008.
-
Abstract
- The AAA+ superfamily is a large superfamily of ATPases that are characterized by a conserved catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes.<br />The AAA+ superfamily is a large and functionally diverse superfamily of NTPases that are characterized by a conserved nucleotide-binding and catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes, attaining this functional diversity through additions of structural motifs and modifications to the core AAA+ module.
- Subjects :
- Genetics
Nucleoside-triphosphatase
0303 health sciences
Binding Sites
030302 biochemistry & molecular biology
SUPERFAMILY
Review
macromolecular substances
Biology
Nucleoside-Triphosphatase
environment and public health
enzymes and coenzymes (carbohydrates)
03 medical and health sciences
Functional diversity
Catalytic Domain
cardiovascular system
cardiovascular diseases
Structural motif
human activities
030304 developmental biology
Subjects
Details
- ISSN :
- 14656906
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Genome Biology
- Accession number :
- edsair.doi.dedup.....f46a6d23f8341645ddb51000cf25f5e0
- Full Text :
- https://doi.org/10.1186/gb-2008-9-4-216