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Patientātailored SyncAV algorithm: A novel strategy to improve synchrony and acute hemodynamic response in heart failure patients treated by cardiac resynchronization therapy
- Source :
- Journal of Cardiovascular Electrophysiology. 31:512-520
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- INTRODUCTION Several automatic algorithms have developed to optimize the timing cycle setting in cardiac resynchronization therapy (CRT). The present study aims to investigate whether the novel device-based SyncAV algorithm could elicit better synchrony and acute hemodynamic response. METHODS AND RESULTS Thirty five patients undergoing CRT implantation were prospectively studied. The device was programmed to three biventricular (BiV) pacing modes sequentially after the procedure: QuickOpt algorithm (mode I), SyncAV algorithm with default 50 ms offset (mode II), and SyncAV algorithm with optimized offset minimizing QRS duration (QRSd) (mode III). After each setting, electrocardiographic and echocardiographic data were collected. As a result, QRSd was reduced from 172.8 ± 17.9 ms during intrinsic conduction to 153.1 ± 15.9 ms in mode I, further narrowed to 140.5 ± 16.7 ms in mode II, and reached shortest (134.8 ± 16.1 ms) in mode III (P .05). Mode I presented significantly higher aortic velocity time integral than intrinsic conduction (21.0 ± 6.4 cm vs 18.4 ± 5.5 cm; P
- Subjects :
- Male
Time Factors
Haemodynamic response
medicine.medical_treatment
Cardiac resynchronization therapy
030204 cardiovascular system & hematology
Ventricular Function, Left
Cardiac Resynchronization Therapy
03 medical and health sciences
QRS complex
0302 clinical medicine
Physiology (medical)
Humans
Medicine
Prospective Studies
030212 general & internal medicine
Aged
Heart Failure
business.industry
Hemodynamics
Recovery of Function
Middle Aged
medicine.disease
Treatment Outcome
Therapy, Computer-Assisted
Heart failure
Ventricular Function, Right
Time to peak
Female
Velocity time integral
Cardiology and Cardiovascular Medicine
business
Algorithm
Algorithms
Subjects
Details
- ISSN :
- 15408167 and 10453873
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiovascular Electrophysiology
- Accession number :
- edsair.doi.dedup.....f4144c39d1f9c1c8a1f0b2d5e2f51982