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State of the Art in Tumor Antigen and Biomarker Discovery
- Source :
- Cancers, Cancers, Vol 3, Iss 2, Pp 2554-2596 (2011)
- Publication Year :
- 2011
- Publisher :
- MDPI AG, 2011.
-
Abstract
- Our knowledge of tumor immunology has resulted in multiple approaches for the treatment of cancer. However, a gap between research of new tumors markers and development of immunotherapy has been established and very few markers exist that can be used for treatment. The challenge is now to discover new targets for active and passive immunotherapy. This review aims at describing recent advances in biomarkers and tumor antigen discovery in terms of antigen nature and localization, and is highlighting the most recent approaches used for their discovery including “omics” technology.
- Subjects :
- Cancer Research
business.industry
medicine.medical_treatment
Passive Immunotherapy
biomarkers
Cancer
Review
Immunotherapy
Computational biology
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Bioinformatics
medicine.disease
Proteomics
lcsh:RC254-282
Tumor antigen
proteomics
Oncology
Antigen
medicine
cancer
immunotherapy
Biomarker discovery
business
Tumor immunology
tumor antigen
Subjects
Details
- ISSN :
- 20726694
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Cancers
- Accession number :
- edsair.doi.dedup.....f3f2bdd949d38bd575705ab5d2b93cbd