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Occupational socioeconomic risk associations for head and neck cancer in Europe and South America: individual participant data analysis of pooled case-control studies within the INHANCE Consortium
- Source :
- Journal of Epidemiology and Community Health, Journal of Epidemiology and Community Health, BMJ Publishing Group, 2021, 75 (8), pp.779-787. ⟨10.1136/jech-2020-214913⟩, Dipòsit Digital de la UB, Universidad de Barcelona, Journal of Epidemiology and Community Health, 2021, 75 (8), pp.779-787. ⟨10.1136/jech-2020-214913⟩, Journal of epidemiology and community health, 75(8):779-787
- Publication Year :
- 2020
-
Abstract
- BackgroundThe association between socioeconomic disadvantage (low education and/or income) and head and neck cancer is well established, with smoking and alcohol consumption explaining up to three-quarters of the risk. We aimed to investigate the nature of and explanations for head and neck cancer risk associated with occupational socioeconomic prestige (a perceptual measure of psychosocial status), occupational socioeconomic position and manual-work experience, and to assess the potential explanatory role of occupational exposures.MethodsPooled analysis included 5818 patients with head and neck cancer (and 7326 control participants) from five studies in Europe and South America. Lifetime job histories were coded to: (1) occupational social prestige—Treiman’s Standard International Occupational Prestige Scale (SIOPS); (2) occupational socioeconomic position—International Socio-Economic Index (ISEI); and (3) manual/non-manual jobs.ResultsFor the longest held job, adjusting for smoking, alcohol and nature of occupation, increased head and neck cancer risk estimates were observed for low SIOPS OR=1.88 (95% CI: 1.64 to 2.17), low ISEI OR=1.74 (95% CI: 1.51 to 1.99) and manual occupations OR=1.49 (95% CI: 1.35 to 1.64). Following mutual adjustment by socioeconomic exposures, risk associated with low SIOPS remained OR=1.59 (95% CI: 1.30 to 1.94).ConclusionsThese findings indicate that low occupational socioeconomic prestige, position and manual work are associated with head and neck cancer, and such risks are only partly explained by smoking, alcohol and occupational exposures. Perceptual occupational psychosocial status (SIOPS) appears to be the strongest socioeconomic factor, relative to socioeconomic position and manual/non-manual work.
- Subjects :
- Data Analysis
medicine.medical_specialty
Epidemiology
Risk factors in diseases
Occupational prestige
[SDV]Life Sciences [q-bio]
Socioeconomic Factor
Head cancer
socioeconomic
Cancer
Cancer Epidemiology
Occupational
Socioeconomic
03 medical and health sciences
0302 clinical medicine
Risk Factors
Epidemiology of cancer
medicine
Humans
030212 general & internal medicine
Socioeconomic status
Càncer de cap
Original Research
business.industry
Factors de risc en les malalties
Prestige
Risk Factor
Head and neck cancer
Public Health, Environmental and Occupational Health
Case-control study
South America
medicine.disease
Neck cancer
Càncer de coll
[SDV] Life Sciences [q-bio]
Europe
Data Analysi
Socioeconomic Factors
cancer: occupational
Head and Neck Neoplasms
030220 oncology & carcinogenesis
Case-Control Studies
cancer epidemiology
business
Case-Control Studie
Psychosocial
Demography
Human
Subjects
Details
- ISSN :
- 14702738 and 0143005X
- Volume :
- 75
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of epidemiology and community health
- Accession number :
- edsair.doi.dedup.....f362c74e602b05ebbfd2d6596630efc3